DISASTER MEDICINE No.1 •2023
https://doi.org/10.33266/2070-1004-2023-1
Original article
Usage of Self-Expanding Polyurethane Foam for Resolving of Ongoing Intra-Abdominal Hemorrhaging in Conditions of Military Conflict and Emergency Situations Basing on an Experience of Tactical-Special Exercises
Reva V.A. 1,2, Goncharov S.F. 3,4, Potemkin V.D. 1, Baranov M.I. 1, Zhabin A.V. 1, Chepur S.V. 5
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1 S.M. Kirov Military Medical Academy of the Russian Ministry of Defense, St. Petersburg, Russia
2 Russian Biotechnological University, Moscow, Russia
3 State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russian Federation
4 Russian Medical Academy of Continuous Professional Education, the Ministry of Health of the Russian Federation, Moscow, Russian Federation
5 State Research and Testing Institute of Military Medicine of the Ministry of Defense of Russia, St. Petersburg, Russia
UDC 616-005.1+615.4+614.88
Pp. 77-82
Summary. Investigation purpose – to evaluate the opportunity, efficiency and safety of usage of national polyurethane foam composition (PFC) during acute experiment taken in the frameworks of conducting of tactical-special exercises (TSE).
Materials and methods of the investigation. Tactical-special military-medical exercises “Ochag” are conducted annually and directed to testing of advanced health care technologies which are perspective for saving solders life and health. For modeling of tactical conditions a time coordinate system of troop system of evacuation of injured was created – from the time of provision medical treatment on artificial battlefield on the frameworks of tactical medicine till the time of provision of primary medical-sanitary treatment in medical platoon and providing of surgery in the frameworks of tactical control of injures in surgical room deployed in a tent of medical company.
Investigation results and their analysis. All animals survived till the end of the experiment, internal hemorrhaging was resolved. Till the 90th minute of experiment an appearance of small values of substances included in the developed foam was noticed in a series of blood analyzes.
This way the first experience of this technology usage during medical treatment provision in tactical time range was got. For assess of this PFC a conducting of pre-clinical and clinical researches was planned.
Key words: animals, emergency situations, experiments, hemostasis, laparotomy, military conflicts, ongoing intra-abdominal hemorrhaging, self-expanding polyurethan foam, tactical-special exercises
Conflict of interest. The authors declare no conflict of interest
For citation: Reva V.A., Goncharov S.F., Potemkin V.D., Baranov M.I., Zhabin A.V., Chepur S.V. Usage of Self-Expanding Polyurethane Foam for Resolving of Ongoing Intra-Abdominal Hemorrhaging in Conditions of Military Conflict and Emergency Situations Basing on an Experience of Tactical-Special Exercises. Meditsina Katastrof = Disaster Medicine. 2023;1:77-82 (In Russ.). https://doi.org/10.33266/2070-1004-2023-1-77-82
REFERENCES
- Samokhvalov I.M., Goncharov A.V., Chirskiy V.S., et al. “Potentially Survivable” Casualties – Reserve to Reduce Pre-Hospital Lethaility in Injuries and Traumas. Skoraya Meditsinskaya Pomoshch’ = Emergency Medical Care. 2019;20;3:10–17 (In Russ.).
- Eastridge B.J., Mabry R.L, Seguin P., et al. Death on the Battlefield (2001-2011): Implications for the Future of Combat Casualty Care. J. Trauma Acute Care Surg. 2012;73;6;Suppl 5:431-437.
- Xu Y., Huang J., Zhou J., et al. Patterns of Abdominal Injury in 37 387 Disaster Patients from the Wenchuan Earthquake. Emerg. Med. 2013;30;7:538–542.
- Reva V.A. Damage Control Resuscitation: what Is it and why? Prakticheskoye rukovodstvo po Damage Control = A Practical Guide to Damage Control. St. Petersburg, R-Kopi Publ.,, 2018. P. 27–50 (In Russ.).
- Rago A.P., Sharma U., Sims K., King D.R. Conceptualized Use of Self-Expanding Foam to Rescue Special Operators from Abdominal Exsanguination: Percutaneous Damage Control for the Forward Deployed. J. Spec. Oper. Med. Peer Rev. J. SOF Med. Prof. 2015;15;3:39–45.
- Holcomb J.B., McClain J.M., Pusateri A.E., et al. Fibrin Sealant Foam Sprayed Directly on Liver Injuries Decreases Blood Loss in Resuscitated Rats. J. Trauma. 2000;49;2:246–250.
- Duggan M., Rago A., Sharma U., et al. Self-Expanding Polyurethane Polymer Improves Survival in a Model of Noncompressible Massive Abdominal Hemorrhage. J. Trauma Acute Care Surg. 2013;74;6:1462–1467.
- Peev M.P., Rago A., Hwabejire J.O., et al. Self-Expanding Foam for Prehospital Treatment of Severe Intra-Abdominal Hemorrhage: Dose Finding Study. J. Trauma Acute Care Surg. 2014;76;3:619–623.
- Rago A., Duggan M.J., Marini J., et al. Self-Expanding Foam Improves Survival Following a Lethal, Exsanguinating Iliac Artery Injury. J. Trauma Acute Care Surg. 2014;77;1:73–77.
- Reva V.A., Litinskiy M.A.. Denisov A.V., et al. First Experience of a Polyurethane foam Composition “Locus” Use to Stop Intra-Abdominal Hemmorage as a Result of Liver Damage of V Degree. (An Experimental Study). Voyenno-Meditsinskiy Zhurnal = Russian Military Medical Journal. 2015;336;4:32–39 (In Russ.).
- Vrancken S.M., Borger van der Burg B., DuBose J.J., et al. Advanced Bleeding Control in Combat Casualty Care: An International, Expert-Based Delphi Consensus. J. Trauma Acute Care Surg. 2022;93;2:256–264.
- Butler F.K., Holcomb J.B., Shackelford S., et al. Advanced Resuscitative Care in Tactical Combat Casualty Care: TCCC Guidelines Change 18-01:14 October 2018. J. Spec. Oper. Med. Peer Rev. J. SOF Med. Prof. 2018;18;4:37–55.
The material was received 17.11.22; the article after peer review procedure 19.01.23; the Editorial Board accepted the article for publication 23.03.23