DISASTER MEDICINE No. 3•2021
Risk of Death from Hypertension among Chernobyl Accident Liquidators – Nuclear Industry Workers
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Tukov A.R.1, Shafranskiy I.L.1, Prokhorova O.N.1, Kalinina M.V.1
1 State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russian Federation
Abstract. The aim of the study was to assess the radiation risk of death from hypertension in liquidators of the Chernobyl nuclear power plant accident consequences — workers of the nuclear industry — using doses from various types of irradiation.
Materials and methods of the study. The study was conducted using data from the Industry Register of Persons exposed to radiation as a result of the Chernobyl accident — workers of the nuclear power industry. Information on 12659 liquidators (all male) was included in the analysis. 1327 of them got occupational radiation doses. Crude relative risks of death from hypertension were estimated for five dose groups using internal controls. Based on the stratified data file, a Poisson regression procedure was performed using the AMFIT module of Epicure program and the excess relative risk of death from hypertension was calculated and the nature of the dose-dependent excess relative mortality was investigated.
Results of the study and their analysis. Direct estimates of radiogenic risk of death from hypertension were obtained. No increase in mortality from hypertensive disease per unit dose was found for both the doses received during the liquidation of the Chernobyl accident consequences and for the total doses. The results of the study can be used in the development of radiation safety regulations for persons working with sources of ionizing radiation.
Keywords: AMFIT, Chernobyl accident, EPICURE, hypertension, industry register, liquidators, nuclear industry workers, radiation, relative risk, risk of death, Rosatom State Corporation, study period
For citation: Tukov A.R., Shafranskiy I.L., Prokhorova O.N., Kalinina M.V.
Risk of Death from Hypertension among Chernobyl Accident Liquidators – Nuclear Industry Workers. Meditsina katastrof = Disaster Medicine. 2021;3:47-51 (In Russ.). https://doi.org/10.33266/2070-1004-2021-3-47-51
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The material was received 18.03.21; the article after peer review procedure 01.05.21; the Editorial Board accepted the article for publication 10.09.21